Dongzhao Chen

Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase

Pan F. Chan, Thomas Germe, B.D. Bax et al. · Proceedings of the National Academy of Sciences · 2017 · 84 citations · Full text

Bioorganic Chemistry, Molecular Biology, Thiophene Inhibitors +17

Novel hydroxyl tricyclics (e.g., GSK966587) as potent inhibitors of bacterial type IIA topoisomerases

Timothy J. Miles, Alan J. Hennessy, B.D. Bax et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 63 citations · Full text

Inhibitory Activity, Medicinal Chemistry, Medicine +13

Novel cyclohexyl-amides as potent antibacterials targeting bacterial type IIA topoisomerases

Timothy J. Miles, Christopher W. Barfoot, Gerald Brooks et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 49 citations · Full text

Medicine, Novel Cyclohexyl-amides, Antibacterial Agent +7

Novel amino-piperidines as potent antibacterials targeting bacterial type IIA topoisomerases

Timothy J. Miles, Jeffrey M. Axten, Christopher W. Barfoot et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 46 citations · Full text

Antibiotics, Medicine, Novel Amino-piperidines +8

Novel tricyclics (e.g., GSK945237) as potent inhibitors of bacterial type IIA topoisomerases

Timothy J. Miles, Alan J. Hennessy, B.D. Bax et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 46 citations · Full text

Novel Tricyclics, Inhibitory Activity, Medicinal Chemistry +12