Lothar Steidler

Treatment of Murine Colitis by <i>Lactococcus lactis</i> Secreting Interleukin-10

Lothar Steidler, Wolfgang Hans, L. Schotte et al. · Science · 2000 · 1.5K citations

Veterinary Medicine, Immunology, Pharmacology +17

A Phase I Trial With Transgenic Bacteria Expressing Interleukin-10 in Crohn’s Disease

Henri Braat, Pieter Rottiers, Daniël W. Hommes et al. · Clinical Gastroenterology and Hepatology · 2006 · 770 citations

Life Sciences, Immunology, Microbiology +14

Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10

Lothar Steidler, Sabine Neirynck, Nathalie Huyghebaert et al. · Nature Biotechnology · 2003 · 539 citations

Life Sciences, Biotechnology, Immunology +11

Orally administered L. lactis secreting an anti-TNF Nanobody demonstrate efficacy in chronic colitis

Klaas Vandenbroucke, Hans de Haard, Els Beirnaert et al. · Mucosal Immunology · 2009 · 284 citations · Full text

Life Sciences, Clinical Sciences, Immunology +14

Active delivery of trefoil factors by genetically modified Lactococcus lactis prevents and heals acute colitis in mice

Klaas Vandenbroucke, Wolfgang Hans, Jacques Van Huysse et al. · Gastroenterology · 2004 · 276 citations · Full text

Life Sciences, Biotechnology, Immunology +14