Hirohiko Kanai

Regulation of c‐Jun N‐terminal kinase, p38 kinase and AP‐1 DNA binding in cultured brain neurons: roles in glutamate excitotoxicity and lithium neuroprotection

Ren‐Wu Chen, Zheng‐Hong Qin, Ming Ren et al. · Journal of Neurochemistry · 2003 · 149 citations · Full text

Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons

Hirohiko Kanai, Akira Sawa, R-W Chen et al. · The Pharmacogenomics Journal · 2004 · 120 citations

Reductive Stress, Medicine, Apoptosis +9

Short-term lithium treatment promotes neuronal survival and proliferation in rat striatum infused with quinolinic acid, an excitotoxic model of Huntington's disease

Vladimir V. Senatorov, Ming‐Yue Ren, Hirohiko Kanai et al. · Molecular Psychiatry · 2003 · 110 citations

Short-term Lithium Treatment, Quinolinic Acid, Medicine +9

Lithium stimulates progenitor proliferation in cultured brain neurons

Ryota Hashimoto, Vladimir V. Senatorov, Hirohiko Kanai et al. · Neuroscience · 2003 · 102 citations

Neurophysiology, Progenitor Proliferation, Neurogenesis +4

Trimethyltin syndrome as a hippocampal degeneration model: temporal changes and neurochemical features of seizure susceptibility and learning impairment

Naoya Ishida, M. Akaike, Shunsuke Tsutsumi et al. · Neuroscience · 1997 · 102 citations

Neuropsychological Functioning, Neuropsychology, Seizure Susceptibility +12