Emily R. Derbyshire

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

Nobutaka Kato, Eamon Comer, Tomoyo Sakata‐Kato et al. · Nature · 2016 · 266 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

A nitric oxide/cysteine interaction mediates the activation of soluble guanylate cyclase

Nathaniel B. Fernhoff, Emily R. Derbyshire, Michael A. Marletta · Proceedings of the National Academy of Sciences · 2009 · 146 citations · Full text

Life Sciences, Biochemistry, Physiology +14

Liver-stage malaria parasites vulnerable to diverse chemical scaffolds

Emily R. Derbyshire, Miguel Prudêncio, Maria M. Mota et al. · Proceedings of the National Academy of Sciences · 2012 · 140 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease

Juliane Totzke, Deepak Gurbani, Rene Raphemot et al. · Cell chemical biology · 2017 · 137 citations · Full text

Medicine, Oncology, Pharmacology +9

The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs

Jonathan D. Herman, Lauren R. Pepper, Joseph F. Cortese et al. · Science Translational Medicine · 2015 · 110 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14