Emily R. Derbyshire

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

Nobutaka Kato, Eamon Comer, Tomoyo Sakata‐Kato et al. · Nature · 2016 · 261 citations · Full text

Diversity-oriented Synthesis Yields, Medicinal Chemistry, Diversity Oriented Synthesis +7

A nitric oxide/cysteine interaction mediates the activation of soluble guanylate cyclase

Nathaniel B. Fernhoff, Emily R. Derbyshire, Michael A. Marletta · Proceedings of the National Academy of Sciences · 2009 · 146 citations · Full text

Nitric Oxide, Molecular Biology, Redox Biology +18

Liver-stage malaria parasites vulnerable to diverse chemical scaffolds

Emily R. Derbyshire, Miguel Prudêncio, Maria M. Mota et al. · Proceedings of the National Academy of Sciences · 2012 · 138 citations · Full text

Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease

Juliane Totzke, Deepak Gurbani, Rene Raphemot et al. · Cell chemical biology · 2017 · 126 citations · Full text

Selective Tak1 Inhibitor, Cancer Immunosurveillance, Autoimmune Disease +11

The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs

Jonathan D. Herman, Lauren R. Pepper, Joseph F. Cortese et al. · Science Translational Medicine · 2015 · 108 citations · Full text