Katie Olson

An Unexpected Synergist Role of P-Glycoprotein and Breast Cancer Resistance Protein on the Central Nervous System Penetration of the Tyrosine Kinase Inhibitor Lapatinib (N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine; GW572016)

Joseph W. Polli, Katie Olson, John P. Chism et al. · Drug Metabolism and Disposition · 2008 · 249 citations

The Role of Efflux and Uptake Transporters in N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions

Joseph W. Polli, Joan E. Humphreys, Kelly A. Harmon et al. · Drug Metabolism and Disposition · 2008 · 248 citations

Evaluation of a chimeric (uPA+/+)/SCID mouse model with a humanized liver for prediction of human metabolism

Mark de Serres, Gary D. Bowers, Gary Boyle et al. · Xenobiotica · 2011 · 34 citations

Metabolomic Profiling, Pharmacological Study, Bioanalysis +22

The comparative disposition and metabolism of dolutegravir, a potent HIV-1 integrase inhibitor, in mice, rats, and monkeys

Lee Moss, David S. Wagner, Eri Kanaoka et al. · Xenobiotica · 2014 · 25 citations