Discovery of a small molecule targeting autophagy via ATG4B inhibition and cell death of colorectal cancer cells in vitro and in vivo

Yuanyuan Fu, Liang Hong, Jiecheng Xu, +12

Autophagy

Soluble egg antigen from Schistosoma japonicum modulates the progression of chronic progressive experimental autoimmune encephalomyelitis via Th2-shift response

Xueping Zheng, Xueqiang Hu, Guoyu Zhou, +4

Journal of Neuroimmunology

Th2-shift ResponseAutoimmune DiseaseAllergySoluble Egg AntigenPathogenesis +10

Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity

Ying Gao, Xueping Zheng, Boyang Chang, +20

Cell Research

Irigenin treatment alleviates doxorubicin (DOX)-induced cardiotoxicity by suppressing apoptosis, inflammation and oxidative stress via the increase of miR-425

Langtao Guo, Xueping Zheng, Enwei Wang, +3

Biomedicine & Pharmacotherapy

Beneficial Role of Neutrophils Through Function of Lactoferrin After Intracerebral Hemorrhage

Xiurong Zhao, Shun‐Ming Ting, Guanghua Sun, +8

Stroke

Combinatorial effects of miR-20a and miR-29b on neuronal apoptosis induced by spinal cord injury.

Xuejun Liu, Xueping Zheng, Rui Zhang, +2

PubMed

ApoptosisCell DeathPathologyInjured Spinal CordSocial Sciences +14

The protease activity of human ATG4B is regulated by reversible oxidative modification

Xueping Zheng, Zuolong Yang, Qianqian Gu, +5

Autophagy

Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy

Weijie Wen, Jianwen Chen, Liugang Ding, +9

Archives of Biochemistry and Biophysics

Cell AutophagyMitophagySignal TransductionUvb-induced Premature SenescenceAutophagy +10

ATG4B inhibitor FMK-9a induces autophagy independent on its enzyme inhibition

Jiaqi Chu, Yuanyuan Fu, Jiecheng Xu, +8

Archives of Biochemistry and Biophysics

Cell AutophagyMitophagySignal TransductionSignaling PathwayAutoantibody Production +7

Excitatory pathway engaging glutamate, calcineurin, and NFAT upregulates IL-4 in ischemic neurons to polarize microglia

Shun‐Ming Ting, Xiurong Zhao, Xueping Zheng, +1

Journal of Cerebral Blood Flow & Metabolism

Il-4 SynthesisImmunologyCell DeathExcitatory PathwaySocial Sciences +19