Jake G. Hoekstra

Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress

Alicia M. Pickrell, Chiu-Hui Huang, Scott R. Kennedy et al. · Neuron · 2015 · 329 citations · Full text

Mitochondrial Function, Genetics, Cell Death +5

P2X7 receptor is critical in α-synuclein–mediated microglial NADPH oxidase activation

Tianfang Jiang, Jake G. Hoekstra, Xin Heng et al. · Neurobiology of Aging · 2015 · 115 citations

Inflammation, Neurodegenerative Diseases, Medicine +11

Mitochondrial DNA mutations increase in early stage Alzheimer disease and are inconsistent with oxidative damage

Jake G. Hoekstra, Michael J. Hipp, Thomas J. Montine et al. · Annals of Neurology · 2016 · 106 citations

Blast exposure causes dynamic microglial/macrophage responses and microdomains of brain microvessel dysfunction

Birgit Huber, J.S. Meabon, Zachary S. Hoffer et al. · Neuroscience · 2016 · 78 citations · Full text

Inflammation, Medicine, Immunology +10

Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma

Jianing Xu, Ed Reznik, Ho‐Joon Lee et al. · eLife · 2019 · 42 citations · Full text

Tumor Biology, Urology, Mitochondrial Function +13