Constitutive aryl hydrocarbon receptor signaling constrains type I interferon–mediated antiviral innate defense

Taisho Yamada, Hiromasa Horimoto, Takeshi Kameyama, +12

Nature Immunology

Antiviral Innate DefenseViral ImmunityImmunologyPathogenesisViral Pathogenesis +7

PARP12, an Interferon-stimulated Gene Involved in the Control of Protein Translation and Inflammation

Iain Welsby, David Hutin, Cyril Gueydan, +3

Journal of Biological Chemistry

Chemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets

Kelsie M. Rodriguez, Sara C. Buch-Larsen, Ilsa T. Kirby, +8

eLife

PARP7 and Mono-ADP-Ribosylation Negatively Regulate Estrogen Receptor α Signaling in Human Breast Cancer Cells

Marit Rasmussen, Susanna Tan, Venkata S. Somisetty, +6

Cells

Breast OncologyParp7 MrnaImmunologyMammary Gland DevelopmentTumor Biology +18

Characterization of TCDD-inducible poly-ADP-ribose polymerase (TIPARP/ARTD14) catalytic activity

Alvin Gomez, Christian Bindesbøll, Somisetty V. Satheesh, +11

Biochemical Journal

The tobacco <i>Ntann12</i> gene, encoding an annexin, is induced upon <i>Rhodoccocus fascians</i> infection and during leafy gall development

Olivier M. Vandeputte, Yves Oukouomi Lowe, Sylvia Burssens, +6

Molecular Plant Pathology

EngineeringNtann12 ExpressionPlant Defense GeneGeneticsRhodoccocus Fascians +19

Hepatocyte-Specific Deletion of TIPARP, a Negative Regulator of the Aryl Hydrocarbon Receptor, Is Sufficient to Increase Sensitivity to Dioxin-Induced Wasting Syndrome

David Hutin, Laura Tamblyn, Alvin Gomez, +8

Toxicological Sciences

Tiparpfl/fl MiceLipid PeroxidationImmunologyDioxin-induced Wasting SyndromeToxicological Mechanism +22

dTIS11 Protein-dependent Polysomal Deadenylation Is the Key Step in AU-rich Element-mediated mRNA Decay in Drosophila Cells

Caroline Vindry, Aurélien Lauwers, David Hutin, +4

Journal of Biological Chemistry

Key StepChromatinDevelopmental BiologyGene RegulationCell Death +5

2,3,7,8-Tetrachlorodibenzo-<i>p</i>-Dioxin (TCDD)-Inducible Poly-ADP-Ribose Polymerase (TIPARP/PARP7) Catalytic Mutant Mice (<i>TiparpH532A</i>) Exhibit Increased Sensitivity to TCDD-Induced Hepatotoxicity and Lethality

David Hutin, Alexandra S. Long, Kim S. Sugamori, +8

Toxicological Sciences

Molecular RegulationCell DeathMolecular BiologyTcdd-induced HepatotoxicityToxicological Mechanism +23

Reduced Colonic Mucosal Injury in 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Poly ADP-Ribose Polymerase (TIPARP/PARP7)-Deficient Mice

David Hutin, Karoline Alvik Hagen, Peng Shao, +3

International Journal of Molecular Sciences