Alastair Hotblack

Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma

Giulia Agliardi, Anna Rita Liuzzi, Alastair Hotblack et al. · Nature Communications · 2021 · 276 citations · Full text

Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4+ T Cells

Anna Śledzińska, Maria Vila de Mucha, Katharina Bergerhoff et al. · Immunity · 2020 · 215 citations · Full text

Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin

Cassandra Stowe, Thomas A. Burley, Helen Allan et al. · eLife · 2019 · 60 citations · Full text

Tunable control of CAR T cell activity through tetracycline mediated disruption of protein–protein interaction

Alastair Hotblack, Evangelia Kokalaki, Morgan J. Palton et al. · Scientific Reports · 2021 · 26 citations · Full text

AKT inhibition generates potent polyfunctional clinical grade AUTO1 CAR T-cells, enhancing function and survival

Vedika Mehra, Giulia Agliardi, Juliana Dias et al. · Journal for ImmunoTherapy of Cancer · 2023 · 24 citations · Full text