Neuromuscular junction instability and altered intracellular calcium handling as early determinants of force loss during unloading in humans

Elena Monti, Carlo Reggiani, Martino V. Franchi, +14

The Journal of Physiology

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

M. Zaeem Cader, Rodrigo Pereira de Almeida Rodrigues, James A. West, +19

Cell

Effects of short‐term unloading and active recovery on human motor unit properties, neuromuscular junction transmission and transcriptomic profile

Fabio Sarto, Daniel W. Stashuk, Martino V. Franchi, +12

The Journal of Physiology

Muscle FunctionNeuromuscular CoordinationMotor ControlNeuromuscular JunctionKinesiology +21

Dietary supplementation with acetyl- l -carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats

Luigi Nicassio, Flavio Fracasso, Giuseppe Sirago, +7

Experimental Gerontology

AgingMitochondrial BiogenesisMedicineLipid PeroxidationPhysiology +7

Growth hormone secretagogues hexarelin and JMV2894 protect skeletal muscle from mitochondrial damages in a rat model of cisplatin-induced cachexia

Giuseppe Sirago, Elena Conte, Flavio Fracasso, +12

Scientific Reports

Increased TFAM binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart

Guglielmina Chimienti, Anna Picca, Giuseppe Sirago, +9

Free Radical Biology and Medicine

Dna DamageLipid PeroxidationMolecular BiologyRedox BiologyEpigenetics +17

Neuromuscular impairment at different stages of human sarcopenia

Fabio Sarto, Martino V. Franchi, Jamie S. McPhee, +15

Journal of Cachexia Sarcopenia and Muscle

Effects of a 2‐year exercise training on neuromuscular system health in older individuals with low muscle function

Elena Monti, Sara Tagliaferri, Sandra Zampieri, +14

Journal of Cachexia Sarcopenia and Muscle

Administration of Enalapril Started Late in Life Attenuates Hypertrophy and Oxidative Stress Burden, Increases Mitochondrial Mass, and Modulates Mitochondrial Quality Control Signaling in the Rat Heart

Anna Picca, Giuseppe Sirago, Vito Pesce, +9

Biomolecules

AgingMitochondrial DysfunctionLipid PeroxidationMitochondrial BiologyLate-life Enalapril Administration +15

“What makes some rats live so long?” The mitochondrial contribution to longevity through balance of mitochondrial dynamics and mtDNA content

Anna Picca, Vito Pesce, Giuseppe Sirago, +3

Experimental Gerontology

BiologyLifespan ExtensionAgingMitochondrial FunctionMitochondrial Contribution +12