Reggie Bosma

Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells

Leigh A. Stoddart, Andrea J. Vernall, Mónica Bouzo-Lorenzo et al. · Scientific Reports · 2018 · 61 citations · Full text

The long duration of action of the second generation antihistamine bilastine coincides with its long residence time at the histamine H1 receptor

Reggie Bosma, Jelle van den Bor, Henry F. Vischer et al. · European Journal of Pharmacology · 2018 · 39 citations · Full text

BRET-based β-arrestin2 recruitment to the histamine H 1 receptor for investigating antihistamine binding kinetics

Reggie Bosma, Ryo Moritani, Rob Leurs et al. · Pharmacological Research · 2016 · 32 citations

Molecular Pharmacology, Biochemistry, Medicine +8

Identification of Ligand Binding Hot Spots of the Histamine H ₁ Receptor following Structure-Based Fragment Optimization

Sebastiaan Kuhne, Albert J. Kooistra, Reggie Bosma et al. · Journal of Medicinal Chemistry · 2016 · 29 citations · Full text

The Target Residence Time of Antihistamines Determines Their Antagonism of the G Protein-Coupled Histamine H1 Receptor

Reggie Bosma, Gesa Witt, Lea Vaas et al. · Frontiers in Pharmacology · 2017 · 29 citations · Full text