Hedgehog signaling maintains chemoresistance in myeloid leukemic cells

Karla Queiroz, Roberta R. Ruela-de-Sousa, Gwenny M. Fuhler, +4

Oncogene

Hematological MalignancyMyelopoiesisMaintains ChemoresistanceMedicineCell Biology +3

Protease‐activated receptor‐1 drives pancreatic cancer progression and chemoresistance

Karla Queiroz, Kun Shi, JanWillem Duitman, +5

International Journal of Cancer

Tumor BiologyOncologyHealth SciencesPancreatic CancerMedicine +9

Activated Protein C Protects Against Myocardial Ischemia/ Reperfusion Injury via Inhibition of Apoptosis and Inflammation

Sarah T.B.G. Loubele, C. Arnold Spek, Peter Leenders, +7

Arteriosclerosis Thrombosis and Vascular Biology

Macrophage-secreted MMP9 induces mesenchymal transition in pancreatic cancer cells via PAR1 activation

Cansu Tekin, Hella L. Aberson, Cynthia Waasdorp, +5

Cellular Oncology

Treatment with an Anti-CD14 Monoclonal Antibody Delays and Inhibits Lipopolysaccharide-Induced Gene Expression in Humans in Vivo

C. Arnold Spek, Annelies Verbon, Hella L. Aberson, +7

Journal of Clinical Immunology

Early macrophage infiltrates impair pancreatic cancer cell growth by TNF-α secretion

Cansu Tekin, Hella L. Aberson, Maarten F. Bijlsma, +1

BMC Cancer

Active site inhibited factor VIIa attenuates myocardial ischemia/reperfusion injury in mice

Sarah T.B.G. Loubele, C. Arnold Spek, Peter Leenders, +7

Journal of Thrombosis and Haemostasis

InflammationMolecular PhysiologyCardiovascular DiseaseReperfusion InjuryMedicine +11

CEBPD Potentiates the Macrophage Inflammatory Response but CEBPD Knock-Out Macrophages Fail to Identify CEBPD-Dependent Pro-Inflammatory Transcriptional Programs

C. Arnold Spek, Hella L. Aberson, Joe M. Butler, +2

Cells

Inflammatory Lung DiseaseLung InflammationImmunologyImmune RegulationImmunologic Mechanism +23

CCAAT/Enhancer-Binding Protein Delta (C/EBPδ): A Previously Unrecognized Tumor Suppressor that Limits the Oncogenic Potential of Pancreatic Ductal Adenocarcinoma Cells

Leonie Hartl, JanWillem Duitman, Hella L. Aberson, +13

Cancers

Ccaat/enhancer-binding Protein δImmunologyPathologyCancer BiologyGlioma +19

FXa-induced intracellular signaling links coagulation to neoangiogenesis: Potential implications for fibrosis

Keren Borensztajn, Hella L. Aberson, Maikel P. Peppelenbosch, +1

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

FibrosisAngiogenesisSignaling PathwayCell SignalingPotential Implications +8