In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges

Beata Turoňová, Mateusz Sikora, Christoph Schürmann, +17

Science

Virus StructureViral ReplicationViral EvolutionSpike ProteinVaccine Development +11

Activation of the Unfolded Protein Response by Lipid Bilayer Stress

Kristina Halbleib, Kristina Pesek, Roberto Covino, +5

Molecular Cell

Proteinlipid InteractionBiochemistryProtein FoldingNatural SciencesUnfolded Protein Response +5

Regulation of lipid saturation without sensing membrane fluidity

Stephanie Ballweg, Erdinç Sezgin, Milka Doktorova, +7

Nature Communications

Computational epitope map of SARS-CoV-2 spike protein

Mateusz Sikora, Sören von Bülow, Florian E.C. Blanc, +3

PLoS Computational Biology

EngineeringViral PathogenesisImmunologyMolecular BiologyPromising Epitope Candidates +15

A Eukaryotic Sensor for Membrane Lipid Saturation

Roberto Covino, Stephanie Ballweg, Claudius Stordeur, +7

Molecular Cell

Proteinlipid InteractionBiochemistryNatural SciencesMembrane BiologyLipid Movement +4

Intrinsic map dynamics exploration for uncharted effective free-energy landscapes

Eliodoro Chiavazzo, Roberto Covino, Ronald R. Coifman, +4

Proceedings of the National Academy of Sciences

Machine-guided path sampling to discover mechanisms of molecular self-organization

Hendrik Jung, Roberto Covino, A. Arjun, +4

Nature Computational Science

Folding Pathways of a Knotted Protein with a Realistic Atomistic Force Field

S. a Beccara, Tatjana Škrbić, Roberto Covino, +2

PLoS Computational Biology

The molecular recognition of phosphatidic acid by an amphipathic helix in Opi1

Harald F. Hofbauer, Michael Gecht, Sabine Fischer, +6

The Journal of Cell Biology

Proteinlipid InteractionPhosphatidic AcidAmphipathic HelixMolecular BiologyLipid Movement +16

Dominant folding pathways of a WW domain

S. a Beccara, Tatjana Škrbić, Roberto Covino, +1

Proceedings of the National Academy of Sciences

Ww Domain Fip35Pattern FormationPhysicsProtein AssemblyProtein Folding +12