Brian Dupré

Novel Synthetic Inhibitors of Selectin-Mediated Cell Adhesion:  Synthesis of 1,6-Bis[3-(3-carboxymethylphenyl)-4-(2-α-<scp>d</scp>-mannopyranosyloxy)phenyl]hexane (TBC1269)

Timothy P. Kogan, Brian Dupré, Huong Thi Bui et al. · Journal of Medicinal Chemistry · 1998 · 128 citations · Full text

Drug Target, Cell Adhesion, Novel Synthetic Inhibitors +17

Rational Design and Synthesis of Small Molecule, Non-oligosaccharide Selectin Inhibitors: (.alpha.-D-Mannopyranosyloxy)biphenyl-Substituted Carboxylic Acids

Timothy P. Kogan, Brian Dupré, Karin M. Keller et al. · Journal of Medicinal Chemistry · 1995 · 85 citations · Full text

Glycobiology, Immunology, Slex-related Oligosaccharide +17

Application of nitrile oxide cycloadditions to a convergent, asymmetric synthesis of (+)-phyllanthocin

Stephen F. Martin, John A. Colapret, Michael S. Dappen et al. · The Journal of Organic Chemistry · 1989 · 66 citations

Chemical Engineering, Nitrile Oxide Cycloadditions, Bioorganic Chemistry +13

Inhibition of adhesion of human neutrophils and eosinophils to P-selectin by the sialyl Lewis x antagonist TBC1269: Preferential activity against neutrophil adhesion in vitro

Kelly L. Davenpeck, Kurt L. Berens, Richard A. F. Dixon et al. · Journal of Allergy and Clinical Immunology · 2000 · 57 citations · Full text

Inflammation, Granulocyte, Medicine +8

Regiochemistry of the dipolar cycloadditions of nitrile oxides to unactivated olefins. Application to the stereoselective elaboration of β-hydroxycarbonyl compounds.

Stephen F. Martin, Brian Dupré · Tetrahedron Letters · 1983 · 51 citations

Chemical Engineering, Engineering, Alkene Metathesis +6