Alternative Macrophage Activation Is Essential for Survival during Schistosomiasis and Downmodulates T Helper 1 Responses and Immunopathology

De’Broski R. Herbert, Christoph Hölscher, Markus Mohrs, +9

Immunity

InflammationAutoimmune DiseaseAllergyImmunologySchistosomiasis +8

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

Carsten O. Daub, Kristoffer Vitting‐Seerup, Robin Andersson, +105

Science

ChromatinTranscriptional RegulationSystems BiologyDevelopmental BiologyFunctional Genomics +13

FANTOM5 CAGE profiles of human and mouse samples

Shuhei Noguchi, Takahiro Arakawa, Shiro Fukuda, +174

Scientific Data

Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation

Hiromasa Morikawa, Naganari Ohkura, Alexis Vandenbon, +267

Proceedings of the National Academy of Sciences

Activated Treg CellsEpigenetic ChangeGeneticsDna MethylationT-regulatory Cell +21

Impairment of Alternative Macrophage Activation Delays Cutaneous Leishmaniasis in Nonhealing BALB/c Mice

Christoph Hölscher, Berenice Arendse, Anita Schwegmann, +2

The Journal of Immunology

IL-4Rα-Independent Expression of Mannose Receptor and Ym1 by Macrophages Depends on their IL-10 Responsiveness

Benjamin G Dewals, Reece Marillier, J. Claire Hoving, +3

PLoS neglected tropical diseases

Protein kinase C δ is essential for optimal macrophage-mediated phagosomal containment of <i>Listeria monocytogenes</i>

Anita Schwegmann, Reto Guler, Antony J. Cutler, +8

Proceedings of the National Academy of Sciences

TH1-Dominant Granulomatous Pathology Does Not Inhibit Fibrosis or Cause Lethality during Murine Schistosomiasis

Mosiuoa Leeto, De’Broski R. Herbert, Reece Marillier, +3

American Journal Of Pathology

Murine SchistosomiasisFibrosisAutoimmune DiseasePathogenesisImmunology +10

IL-4Rα-Dependent Alternative Activation of Macrophages Is Not Decisive for Mycobacterium tuberculosis Pathology and Bacterial Burden in Mice

Reto Guler, Suraj P. Parihar, Suzana Savvi, +8

PLoS ONE

Microbial PathogensImmunologyImmune RegulationCd4 T Cell ResponsesInnate Immunity +19

PKCδ regulates IL‐12p40/p70 production by macrophages and dendritic cells, driving a type 1 healer phenotype in cutaneous leishmaniasis

Reto Guler, Mona Afshar, Berenice Arendse, +5

European Journal of Immunology

Immune RegulationImmunologyImmunologic MechanismInnate ImmunityDermatology +19