Progressive Disruption of Cellular Protein Folding in Models of Polyglutamine Diseases

Tali Gidalevitz, Anat Ben‐Zvi, Kim H. Ho, +2

Science

Protein AssemblyProgressive DisruptionPolyglutamine ExpansionsMolecular BiologyCytoskeleton +15

Protein Disulfide Isomerase A6 Controls the Decay of IRE1α Signaling via Disulfide-Dependent Association

Davide Eletto, Daniela Eletto, Devin Dersh, +2

Molecular Cell

Protein FunctionSignal TransductionBiochemistryMolecular RegulationNatural Sciences +7

Destabilizing Protein Polymorphisms in the Genetic Background Direct Phenotypic Expression of Mutant SOD1 Toxicity

Tali Gidalevitz, Thomas Krupinski, Susana M. D. A. Garcia, +1

PLoS Genetics

GeneticsHuman PolymorphismMolecular BiologyMolecular GeneticsDisease Gene Identification +18

GRP94 Is Essential for Mesoderm Induction and Muscle Development Because It Regulates Insulin-like Growth Factor Secretion

Sherry Wanderling, Birgitte B. Simen, Olga Ostrovsky, +4

Molecular Biology of the Cell

Muscle DevelopmentCellular PhysiologyInsulin SignalingEmbryologySkeletal Muscle +18

Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation

Alexandra Zourlidou, Tali Gidalevitz, Mark Kristiansen, +8

Human Molecular Genetics

Mitochondrial DysfunctionExpanded Polyglutamine TractCell DeathMolecular BiologyNeurochemical Biomarkers +16

The peptide-binding activity of GRP94 is regulated by calcium

Chhanda Biswas, Olga Ostrovsky, Catherine A. Makarewich, +3

Biochemical Journal

Radicicol-sensitive Peptide Binding to the N-terminal Portion of GRP94

Shawn M. Vogen, Tali Gidalevitz, Chhanda Biswas, +4

Journal of Biological Chemistry

Protein AssemblyMolecular BiologyRadicicol-sensitive Peptide BindingPeptide BindingSeveral Peptides +16

Identification of the N-terminal Peptide Binding Site of Glucose-regulated Protein 94

Tali Gidalevitz, Chhanda Biswas, Hua Ding, +5

Journal of Biological Chemistry

Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans

Suraiya Haroon, Annie Li, Jaye L. Weinert, +8

Cell Reports

Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegansmodel for polyglutamine disease

Tali Gidalevitz, Ning Wang, Tanuja Deravaj, +2

BMC Biology