Tokuichi Takagi

Effect of a new potent H2-blocker, 3-]]]2-[(diaminomethylene)amino]-4-thiazolyl]methyl]-thio]-N2-sulfamoylpropionamidine (YM-11170) on gastric secretion induced by histamine and food in conscious dogs.

Tokuichi Takagi, Midori Takeda, Hiroo Maeno · PubMed · 1982 · 46 citations

Gastric Acid Response, Gastrointestinal Pharmacology, Gastroenterology +16

Effect of a new potent H2-blocker, 3-[[[2-(diaminomethylene)amino]-4-thiazolyl]methyl]thio]-N2-sulfamoyl propionamidine (YM-11170), on gastric secretion, ulcer formation and weight of male accessory sex organs in rats.

Masaaki Takeda, Tokuichi Takagi, Yasunori Yashima et al. · PubMed · 1982 · 42 citations

Medicinal Chemistry, Ym 11170, Gastric Secretion +13

Kinetics of antisecretory action of a new H2-antagonist, YM-11170, in conscious dogs

Masaaki Takeda, Tokuichi Takagi, Hiroo Maeno · European Journal of Pharmacology · 1983 · 20 citations

Animal Physiology, Neuropeptides, Antisecretory Action +7

H2-blocking and antisecretory activity of 3[[[2-(diaminomethylene) amino]-4-thiazolyl]methyl]-N-sulfamoylpropionamidine (YM-11170) in anesthetized dogs

Masaaki Takeda, Tokuichi Takagi, Hiroo Maeno · The Japanese Journal of Pharmacology · 1981 · 11 citations · Full text

Animal Physiology, Anaesthetic Agent, Anesthetized Dogs +9

Studies on prostaglandins. VI. Synthesis of 16(S)-methyl-20-methoxy-PGE2 (YPG-209) having oral bronchodilator activity and its analogs.

Hidenori Iwamoto, N. INUKAI, Isao Yanagisawa et al. · Chemical and Pharmaceutical Bulletin · 1980 · 10 citations · Full text

Asthma, Molecular Pharmacology, Medicinal Chemistry +13