Florent Toscano

Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling

Alejandra Garcia-Cattaneo, François-Xavier Gobert, Mélanie Müller et al. · Proceedings of the National Academy of Sciences · 2012 · 177 citations · Full text

Innate Immune System, Immunology, Cell Death +24

dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8

Yann Estornes, Florent Toscano, François Virard et al. · Cell Death and Differentiation · 2012 · 158 citations · Full text

Dsrna Induces, Atypical Death Complex, Medicine +9

Cleaved/Associated TLR3 Represents the Primary Form of the Signaling Receptor

Florent Toscano, Yann Estornes, François Virard et al. · The Journal of Immunology · 2012 · 65 citations

p53 dependent and independent sensitivity to oxaliplatin of colon cancer cells

Florent Toscano, B. Parmentier, Zineb El Fajoui et al. · Biochemical Pharmacology · 2007 · 56 citations

Tumor Biology, Medicine, Colon Cancer Cells +10

p53-Mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic anti-tumour potential in colon cancer cells

Florent Toscano, Zineb El Fajoui, F. Gay et al. · Oncogene · 2008 · 43 citations

Oncology, Medicine, Colon Cancer Cells +8