Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3

Yuang-T. Juang, William Lowther, Merrill J. Kellum, +4

Proceedings of the National Academy of Sciences

GeneticsImmunologyGene Regulatory NetworkPrimary ActivationTranscriptional Regulation +19

Multiple Regulatory Domains of IRF-5 Control Activation, Cellular Localization, and Induction of Chemokines That Mediate Recruitment of T Lymphocytes

Betsy Barnes, Merrill J. Kellum, Ann E. Field, +1

Molecular and Cellular Biology

Cellular LocalizationT-regulatory CellImmunologyImmune RegulationViral Pathogenesis +21

Functional Analysis of Human Herpesvirus 8-Encoded Viral Interferon Regulatory Factor 1 and Its Association with Cellular Interferon Regulatory Factors and p300

Ladislav Burýšek, Wen-Shuz Yeow, Barbora Lubyová, +4

Journal of Virology

Interferon regulatory factor 5, a novel mediator of cell cycle arrest and cell death.

Betsy Barnes, Merrill J. Kellum, Karen Pinder, +2

PubMed

Novel MediatorApoptosisImmunologyImmune RegulationCell Death +18

ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation.

Gang Lu, Thomas Reinert, Ian Pitha, +5

PubMed

ImmunologyViral PathogenesisInnate ImmunityAntiviral DrugImmunotherapy +16

The IRS-pathway operates distinctively from the Stat-pathway in hematopoietic cells and transduces common and distinct signals during engagement of the insulin or interferon-alpha receptors.

Shahab Uddin, Eleanor N. Fish, Dorie Sher, +6

PubMed

Kaposi's Sarcoma-associated Herpesvirus-encoded vIRF-3 Stimulates the Transcriptional Activity of Cellular IRF-3 and IRF-7

Barbora Lubyová, Merrill J. Kellum, Augusto Frisancho, +1

Journal of Biological Chemistry

Differential Use of the βL Subunit of the Type I Interferon (IFN) Receptor Determines Signaling Specificity for IFNα2 and IFNβ

Paul Domanski, Owen W. Nadeau, Leonidas C. Platanias, +4

Journal of Biological Chemistry

Stimulation of c-Myc Transcriptional Activity by vIRF-3 of Kaposi Sarcoma-associated Herpesvirus

Barbora Lubyová, Merrill J. Kellum, J. Augusto Frisancho, +1

Journal of Biological Chemistry

ImmunologyPathologyTumor BiologyViral OncologyCancer-associated Virus +16

Upstream Regulatory Elements of Murine α4-Interferon Gene Confer Inducibility and Cell Type-restricted Expression

Nitin Raj, Ron Israeli, Merrill J. Kellum, +1

Journal of Biological Chemistry