Tumor-Microenvironment-Activatable Nanoparticle Mediating Immunogene Therapy and M2 Macrophage-Targeted Inhibitor for Synergistic Cancer Immunotherapy

Yuzhu Hu, Wen Nie, Liang Lyu, +9

ACS Nano

TBBPA regulates calcium-mediated lysosomal exocytosis and thereby promotes invasion and migration in hepatocellular carcinoma

Liang Lyu, Xiaoting Jin, Zhuoyu Li, +4

Ecotoxicology and Environmental Safety

Tumor BiologyCalcium-mediated Lysosomal ExocytosisMedicineLiver PhysiologyPathology +7

TBBPA stimulated cell migration of endometrial cancer via the contribution of NOX-generated ROS in lieu of energy metabolism

Huilan Su, Ge Guan, Rifat Zubair Ahmed, +3

Journal of Hazardous Materials

Nox-generated RosCell MigrationMetabolic RemodelingCell BiologyTumor Suppressor +5

Single-cell sequencing of PIT1-positive pituitary adenoma highlights the pro-tumour microenvironment mediated by IFN-γ-induced tumour-associated fibroblasts remodelling

Liang Lyu, Yong Jiang, Weichao Ma, +9

British Journal of Cancer

OncologyPituitary GlandMedicineIfn-γ-induced Tumour-associated FibroblastsCancer Cell Biology +9

Incidence, demographics, and survival of patients with primary pituitary tumors: a SEER database study in 2004–2016

Cheng Chen, Yu Hu, Liang Lyu, +4

Scientific Reports

TDO2 and tryptophan metabolites promote kynurenine/AhR signals to facilitate glioma progression and immunosuppression.

Chuanhong Zhong, Lilei Peng, Bei Tao, +7

PubMed

Exosomal miRNA Profiling is a Potential Screening Route for Non-Functional Pituitary Adenoma

Liang Lyu, Haiyan Li, Cheng Chen, +7

Frontiers in Cell and Developmental Biology

EngineeringPathologyHuman MirnaNon-functional Pituitary AdenomasEpigenetics +19

Overexpression of SIRT1 is a poor prognostic factor for advanced colorectal cancer

Kewei Jiang, Liang Lyu, Zhanlong Shen, +6

Chinese Medical Journal

Hyperprolactinemia in clinical non-functional pituitary macroadenomas

Liang Lyu, Senlin Yin, Yu Hu, +7

Medicine

UrologyPituitary GlandEndocrine DiseaseDiabetesNeuroendocrine Disorder +10

PAK inhibitor FRAX486 decreases the metastatic potential of triple-negative breast cancer cells by blocking autophagy

Liang Lyu, Haiyan Li, Kefeng Lu, +2

British Journal of Cancer