TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity

Aolin Jia, Shijia Huang, Wen Song, +20

Science

EngineeringPlant Defense GeneImmunologyInnate ImmunityBiosynthesis +15

Identification and receptor mechanism of TIR-catalyzed small molecules in plant immunity

Shijia Huang, Aolin Jia, Wen Song, +17

Science

Plant Defense GeneImmunologyMolecular BiologyPlant Defence ActivatorReceptor Mechanism +16

Discovery of Dosimertinib, a Highly Potent, Selective, and Orally Efficacious Deuterated EGFR Targeting Clinical Candidate for the Treatment of Non-Small-Cell Lung Cancer

Yonggang Meng, Bin Yu, He Huang, +10

Journal of Medicinal Chemistry

A canonical protein complex controls immune homeostasis and multipathogen resistance

Yue Wu, Weiying Xu, Guoyan Zhao, +22

Science

Identification and receptor mechanism of TIR-catalyzed small molecules in plant immunity

Shijia Huang, Aolin Jia, Wen Song, +17

Environmental SignalingMolecular BiologyPlant Molecular BiologyPlant Defence ActivatorReceptor Mechanism +16

TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity

Aolin Jia, Shijia Huang, Wen Song, +20

Plant Defense GeneImmunologyInnate ImmunityPlant Molecular BiologyTranscriptional Regulation +16

Synthesis of 5-<i>epi</i>-Taiwaniaquinone G

Jinqian Wang, Jing Wang, Changwei Li, +4

The Journal of Organic Chemistry

Combinatorial ChemistryMedicinal ChemistryBioorganic ChemistryHeterocyclicBiochemistry +9

Brozopine Inhibits 15-LOX-2 Metabolism Pathway After Transient Focal Cerebral Ischemia in Rats and OGD/R-Induced Hypoxia Injury in PC12 Cells

Yuan Gao, Xinyu Cao, Xiaojiao Zhang, +4

Frontiers in Pharmacology

AlCl3-promoted three-component cascade reaction for rapid access to [1,2,3]triazolo[5,1-a]isoquinolines

Yangang Wu, Yonggang Meng, Zibo Liu, +2

Tetrahedron Letters

HeterocyclicRapid AccessOrganic ChemistryChemistryHeterocycle Chemistry

Synthesis of isoindolo[1,2-a]isoquinoline and isoindolo[2,1-a]quinoline derivatives via trifluoroacetic acid-mediated cascade reactions

Zhuo Huang, Yonggang Meng, Yangang Wu, +2

Tetrahedron

Organic ChemistryStereoselective SynthesisChemistryHeterocycle ChemistryPharmacology +2