Laura S. Bess

Novel Lipidated Imidazoquinoline TLR7/8 Adjuvants Elicit Influenza-Specific Th1 Immune Responses and Protect Against Heterologous H3N2 Influenza Challenge in Mice

Shannon M. Miller, Van Cybulski, Margaret Whitacre et al. · Frontiers in Immunology · 2020 · 59 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Studies of Pyrrolo[1,2-<i>a</i>]benzimidazolequinone DT-Diaphorase Substrate Activity, Topoisomerase II Inhibition Activity, and DNA Reductive Alkylation

Edward B. Skibo, Samantha C. Gordon, Laura S. Bess et al. · Journal of Medicinal Chemistry · 1997 · 38 citations

Life Sciences, Molecular Biology, Pharmacology +13

The Organic Chemistry of the Pyrrolo[1,2-a]benzimidazole Antitumor Agents. An Example of Rational Drug Design

Edward B. Skibo, Imadul Islam, WILLIAM G. SCHULZ et al. · Synlett · 1996 · 33 citations

Medicine, Medicinal Chemistry, Oncology +12

The ‘Ethereal’ nature of TLR4 agonism and antagonism in the AGP class of lipid A mimetics

Hélène G. Bazin, Tim J. Murray, William S. Bowen et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 28 citations · Full text

Life Sciences, Immunology, Pharmacology +12

Synthetic Toll-like Receptors 7 and 8 Agonists: Structure–Activity Relationship in the Oxoadenine Series

Jay T. Evans, Laura S. Bess, Sandra C. Mwakwari et al. · ACS Omega · 2019 · 21 citations · Full text

Life Sciences, Immunology, Medicinal Chemistry +17