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Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections

Bin Liu, Robert E. Lee Trout, Guo‐Hua Chu et al. · Journal of Medicinal Chemistry · 2019 · 298 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in <i>Enterobacterales</i> and Pseudomonas aeruginosa

Jodie C. Hamrick, Jean‐Denis Docquier, Tsuyoshi Uehara et al. · Antimicrobial Agents and Chemotherapy · 2019 · 213 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

In vitro activity of the tribactam GV104326 against gram-positive, gram-negative, and anaerobic bacteria

Enza Di Modugno, Isabelle Erbetti, Luc Ferrari et al. · Antimicrobial Agents and Chemotherapy · 1994 · 101 citations · Full text

Life Sciences, Microbiology, Pharmacology +17

Discovery of VNRX-7145 (VNRX-5236 Etzadroxil): An Orally Bioavailable β-Lactamase Inhibitor for Enterobacterales Expressing Ambler Class A, C, and D Enzymes

Robert E. Lee Trout, Allison L. Zulli, Eugen F. Mesaros et al. · Journal of Medicinal Chemistry · 2021 · 47 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Ceftazidime in treatment of acute pulmonary exacerbations in patients with cystic fibrosis

Rita Padoan, A Brienza, Rosa Maria Crossignani et al. · The Journal of Pediatrics · 1983 · 36 citations

Medicine, Pharmacology, Pharmacotherapy +11