Hirotsugu Maekawa

In vitro bone-like nodules generated from patient-derived iPSCs recapitulate pathological bone phenotypes

Shunsuke Kawai, Hiroyuki Yoshitomi, Junko Sunaga et al. · Nature Biomedical Engineering · 2019 · 80 citations

Medicine, Orthopedic Surgery, Pathology +15

An osteoinductive and biodegradable intramedullary implant accelerates bone healing and mitigates complications of bone transport in male rats

Sien Lin, Hirotsugu Maekawa, Seyedsina Moeinzadeh et al. · Nature Communications · 2023 · 30 citations · Full text

Medicine, Orthopaedic Surgery, Surgery +17

Prophylactic treatment of rapamycin ameliorates naturally developing and episode -induced heterotopic ossification in mice expressing human mutant ACVR1

Hirotsugu Maekawa, Shunsuke Kawai, Megumi Nishio et al. · Orphanet Journal of Rare Diseases · 2020 · 22 citations · Full text

Life Sciences, Pathobiology, Pharmacotherapy +14

Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs

Hirotsugu Maekawa, Yonghui Jin, Megumi Nishio et al. · Orphanet Journal of Rare Diseases · 2022 · 10 citations · Full text

Life Sciences, Cell Biology, Pathology +15