Hannah R. Lyford

Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model

Katherine A. Waugh, Ross Minter, Jessica Baxter et al. · Nature Genetics · 2023 · 112 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

JAK inhibition decreases the autoimmune burden in Down syndrome

Angela L. Rachubinski, Elizabeth Wallace, Emily Gurnee et al. · eLife · 2024 · 26 citations · Full text

Life Sciences, Immunology, Pharmacology +10

Variegated overexpression of chromosome 21 genes reveals molecular and immune subtypes of Down syndrome

Micah G. Donovan, Neetha Paul Eduthan, Keith P. Smith et al. · Nature Communications · 2024 · 24 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Interferon receptor gene dosage determines diverse hallmarks of Down syndrome

Katherine A. Waugh, Ross Minter, Jessica Baxter et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 13 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Multimodal analysis of dysregulated heme metabolism, hypoxic signaling, and stress erythropoiesis in Down syndrome

Micah G. Donovan, Angela L. Rachubinski, Keith P. Smith et al. · Cell Reports · 2024 · 11 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17