Paul Yan

APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases

Opeyemi A. Olabisi, Jia-Yue Zhang, Lynn VerPlank et al. · Proceedings of the National Academy of Sciences · 2015 · 235 citations · Full text

Medicine, Molecular Genetics, Nephrology +16

A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system

Julia F. Alterman, Bruno M.D.C. Godinho, Matthew Hassler et al. · Nature Biotechnology · 2019 · 229 citations

Life Sciences, Molecular Biology, Neuroscience +16

<i>UBD</i> modifies <i>APOL1</i> -induced kidney disease risk

Jia-Yue Zhang, Minxian Wang, Lei Tian et al. · Proceedings of the National Academy of Sciences · 2018 · 69 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Comparative expression of the extracellular calcium-sensing receptor in the mouse, rat, and human kidney

João Graça, Martin Schepelmann, Sarah C. Brennan et al. · American Journal of Physiology-Renal Physiology · 2015 · 63 citations · Full text

Life Sciences, Molecular Biology, Physiology +14

RD3 gene delivery restores guanylate cyclase localization and rescues photoreceptors in the Rd3 mouse model of Leber congenital amaurosis 12

Laurie L. Molday, Hidayat R. Djajadi, Paul Yan et al. · Human Molecular Genetics · 2013 · 54 citations · Full text

Medicine, Genetics, Molecular Biology +17