James Locke

Oxidation of the phosphine from the auranofin analog, triisopropylphosphine(2,3,4,6-tetra-O-acetyl-1-thio-.beta.-D-glucopyranosato-S)gold(I), via a protein-bound phosphonium intermediate

C. Frank Shaw, Anvarhusein A. Isab, James D. Hoeschele et al. · Journal of the American Chemical Society · 1994 · 42 citations

Natural Sciences, Biochemistry, Chemistry +7

Reactions of trimethylphosphine analogs of auranofin with bovine serum albumin

Anvarhusein A. Isab, C. Frank Shaw, James D. Hoeschele et al. · Inorganic Chemistry · 1988 · 26 citations

Pharmacy, Biochemistry, Medicinal Chemistry +6

GC-MS and oxygen-17 NMR tracer studies of triethylphosphine oxide formation from auranofin and water-17O in the presence of bovine serum albumin: an in vitro model for auranofin metabolism

Anvarhusein A. Isab, C. Frank Shaw, James Locke · Inorganic Chemistry · 1988 · 17 citations

Natural Sciences, Biochemistry, Chemistry +6