Tim Daynard

Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth

Lincoln Edwards, Brian Thiessen, Wieslawa H. Dragowska et al. · Oncogene · 2005 · 104 citations

Medicine, Cancer Biology, Oncology +14

QLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatment outcomes in an orthotopic breast cancer model

Jessica Kalra, Corinna Warburton, Karen Fang et al. · Breast Cancer Research · 2009 · 74 citations · Full text

Medicine, Oncology, Pharmacology +17

Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of Integrin-linked kinase (ILK)

Lincoln Edwards, Janet Woo, Lynsey A. Huxham et al. · Molecular Cancer Therapeutics · 2008 · 62 citations

Medicine, Cancer Biology, Pharmacology +17