Da Hyun Lee

SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity

Da Hyun Lee, Jeong Su Park, Yu Seol Lee et al. · Autophagy · 2020 · 252 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis

Da Hyun Lee, Dai Hoon Han, Ki Taek Nam et al. · Free Radical Biology and Medicine · 2016 · 93 citations · Full text

Medicine, Molecular Medicine, Pharmacology +9

A GLP‐1/GLP‐2 receptor dual agonist to treat NASH: Targeting the gut‐liver axis and microbiome

Eun Ran Kim, Jeong Su Park, Jin Hee Kim et al. · Hepatology · 2021 · 75 citations · Full text

Life Sciences, Pharmacology, Pharmacotherapy +17

Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity

Jeong Su Park, Da Hyun Lee, Yu Seol Lee et al. · Autophagy · 2019 · 50 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

A synthetic chalcone, 2'-hydroxy-2,3,5'-trimethoxychalcone triggers unfolded protein response-mediated apoptosis in breast cancer cells

Da Hyun Lee, You Jung Jung, Dongsoo Koh et al. · Cancer Letters · 2015 · 42 citations

Life Sciences, Cell Biology, Oncology +11