Gen Takagi

Aging Increases Aortic MMP-2 Activity and Angiotensin II in Nonhuman Primates

Mingyi Wang, Gen Takagi, Kuniya Asai et al. · Hypertension · 2003 · 230 citations

Hypertension, Vascular Disease, Aging +17

Disruption of type 5 adenylyl cyclase gene preserves cardiac function against pressure overload

Satoshi Okumura, Gen Takagi, Jun-ichi Kawabe et al. · Proceedings of the National Academy of Sciences · 2003 · 199 citations · Full text

Peripheral Vascular Endothelial Dysfunction and Apoptosis in Old Monkeys

Kuniya Asai, Raymond K. Kudej, You-Tang Shen et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2000 · 189 citations · Full text

Cyclosporine Attenuates Pressure-Overload Hypertrophy in Mice While Enhancing Susceptibility to Decompensation and Heart Failure

Tomomi Meguro, Chull Hong, Kuniya Asai et al. · Circulation Research · 1999 · 179 citations

Inflammation, Animal Physiology, Heart Failure +13

The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy

Junichi Sadoshima, Olivier Montagne, Qian Wang et al. · Journal of Clinical Investigation · 2002 · 168 citations · Full text

Cardiac Muscle, Heart Failure, Cell Death +18