George Rucci

Distribution, excretion, and metabolism of 2,3,7,8-tetrachlorodibenzo-p-dioxin in C57BL/6J, DBA/2J, and B6D2F1/J mice.

Thomas A. Gasiewicz, Lee E. Geiger, George Rucci et al. · Drug Metabolism and Disposition · 1983 · 187 citations

Pharmacy, Pharmacokinetics, Toxicology +10

Analysis of structural requirements for ah receptor antagonist activity: Ellipticines, flavones, and related compounds

Thomas A. Gasiewicz, Andrew S. Kende, George Rucci et al. · Biochemical Pharmacology · 1996 · 142 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Alpha-naphthoflavone acts as an antagonist of 2,3,7, 8-tetrachlorodibenzo-p-dioxin by forming an inactive complex with the Ah receptor.

Thomas A. Gasiewicz, George Rucci · PubMed · 1991 · 135 citations

Life Sciences, Biochemistry, Pharmacology +11

Cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Evidence for a homologous nature among various mammalian species.

Thomas A. Gasiewicz, George Rucci · Molecular Pharmacology · 1984 · 134 citations

Pharmacy, Pharmacology, Toxicology +13

Flavone Antagonists Bind Competitively with 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) to the Aryl Hydrocarbon Receptor But Inhibit Nuclear Uptake and Transformation

Ellen C. Henry, Andrew S. Kende, George Rucci et al. · Molecular Pharmacology · 1999 · 129 citations

Medicine, Medicinal Chemistry, Pharmacology +16