Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Michael P. Menden, Dennis Wang, Mike J. Mason, +345

Nature Communications

Minimal functional driver gene heterogeneity among untreated metastases

Johannes G. Reiter, Alvin P. Makohon-Moore, Jeffrey M. Gerold, +13

Science

Untreated MetastasesEngineeringPathologyCancer BiologyTreatment-naïve Metastases +14

Ad26/MVA therapeutic vaccination with TLR7 stimulation in SIV-infected rhesus monkeys

Erica N. Borducchi, Crystal Cabral, Kathryn E. Stephenson, +25

Nature

VaccinationTlr7 StimulationMucosal VaccinationVaccine DevelopmentVaccine Target +4

Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis

Alexander Heyde, David Rohde, Cameron S. McAlpine, +16

Cell

MedicineHematologyStem Cell ResearchVascular BiologyStem Cell Proliferation +5

Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane

Zheng Wang, Evelyn Gurule, Timothy Brennan, +11

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyViral DynamicMolecular BiologyReplication-competent Hiv-1 Persist +14

Reconstructing metastatic seeding patterns of human cancers

Johannes G. Reiter, Alvin P. Makohon-Moore, Jeffrey M. Gerold, +5

Nature Communications

Treeomics InfersEngineeringIllusory Tumour HeterogeneityGenomicsTumor Biology +18

TLR7 agonists induce transient viremia and reduce the viral reservoir in SIV-infected rhesus macaques on antiretroviral therapy

So‐Yon Lim, Christa E. Osuna, Peter Hraber, +12

Science Translational Medicine

Quantifying Clonal and Subclonal Passenger Mutations in Cancer Evolution

Ivana Božić, Jeffrey M. Gerold, Martin A. Nowak

PLoS Computational Biology

Cancer EvolutionEngineeringSomatic VariantTumor HeterogeneityMedicine +9

The Evolutionary Origins of Recurrent Pancreatic Cancer

Hitomi Sakamoto, Marc A. Attiyeh, Jeffrey M. Gerold, +19

Cancer Discovery

Precancerous neoplastic cells can move through the pancreatic ductal system

Alvin P. Makohon-Moore, Karen Matsukuma, Ming Zhang, +14

Nature

Tumor BiologyPancreatic CancerHistopathologyPathologyPancreatic Surgery +4