MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies

Gaurav S. Choudhary, Sayer Al-harbi, Suparna Mazumder, +5

Cell Death and Disease

ImmunologyMtor PathwaysImmunotherapyBcl-2 Inhibitor Abt-199Tumor Biology +14

The adult penile urethra is a novel entry site for HIV-1 that preferentially targets resident urethral macrophages

Yonatan Ganor, Zhicheng Zhou, Juraj Bodo, +7

Mucosal Immunology

Sexual HealthUrologyUrological ResearchNeurovirologyHuman Retrovirus +6

Combination of ibrutinib with <scp>ABT</scp>‐199: synergistic effects on proliferation inhibition and apoptosis in mantle cell lymphoma cells through perturbation of <scp>BTK</scp>,<scp> AKT</scp> and <scp>BCL</scp>2 pathways

Xiaoxian Zhao, Juraj Bodo, Danyu Sun, +4

British Journal of Haematology

Bcl2 FamilyApoptosisImmunologyCell DeathImmunotherapy +19

CpG methylation patterns and decitabine treatment response in acute myeloid leukemia cells and normal hematopoietic precursors

Soledad Negrotto, Kwok Peng Ng, Anna Jankowska, +7

Leukemia

Hematological MalignancyChromatinCpg Methylation PatternsNormal Hematopoietic PrecursorsEpigenetic Change +12

Resistance to BTK inhibition by ibrutinib can be overcome by preventing FOXO3a nuclear export and PI3K/AKT activation in B-cell lymphoid malignancies

Isha Kapoor, Yue Li, Arishya Sharma, +6

Cell Death and Disease

Angioimmunoblastic T-cell Lymphomas With the RHOA p.Gly17Val Mutation Have Classic Clinical and Pathologic Features

Sarah L. Ondrejka, Bartosz Grzywacz, Juraj Bodo, +6

The American Journal of Surgical Pathology

ImmunologyPathologyImmunotherapyTumor BiologyHematological Malignancy +15

Acquired resistance to venetoclax (ABT-199) in<i>t(14;18)</i>positive lymphoma cells

Juraj Bodo, Xiaoxian Zhao, Lisa Durkin, +4

Oncotarget

Flavonoid quercetin, but not apigenin or luteolin, induced apoptosis in human myeloid leukemia cells and their resistant variants.

J Duraj, K Zazrivcova, Juraj Bodo, +2

PubMed

Chemoprevention StrategyApoptosisCell DeathPharmacotherapyTumor Biology +16

Effect of Isothiocyanates on Nuclear Accumulation of NF-κB, Nrf2, and Thioredoxin in Caco-2 Cells

Jana Jakubı́ková, Ján Sedlák, Juraj Bodo, +1

Journal of Agricultural and Food Chemistry

Inflammatory Lung DiseaseLung InflammationReactive Oxygen SpeciesRedox BiologyCellular Physiology +19

GATA4 loss of function in liver cancer impedes precursor to hepatocyte transition

Francis Enane, Timothy Wai Ho Shuen, Xiaorong Gu, +26

Journal of Clinical Investigation

GeneticsGata4 LossTumor BiologyHepatobiliary TumorRadiation Oncology +15