Leonard Lothstein

Taxol: Mechanisms of Action and Resistancea

Susan Band Horwitz, Leonard Lothstein, James J. Manfredi et al. · Annals of the New York Academy of Sciences · 1986 · 417 citations

Biochemistry, Mechanism Of Action, Secondary Metabolite +2

Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells

S Hsu, Leonard Lothstein, Susan Band Horwitz · Journal of Biological Chemistry · 1989 · 238 citations · Full text

Knockout Mouse, Differential Overexpression, Systems Biology +14

ATM and the Catalytic Subunit of DNA-Dependent Protein Kinase Activate NF-κB through a Common MEK/Extracellular Signal-Regulated Kinase/p90^<i>rsk</i> Signaling Pathway in Response to Distinct Forms of DNA Damage

Ganesh R. Panta, Swayamjot Kaur, Lakita G. Cavin et al. · Molecular and Cellular Biology · 2004 · 126 citations · Full text

Structural analysis of the mouse mdr1a (P-glycoprotein) promoter reveals the basis for differential transcript heterogeneity in multidrug-resistant J774.2 cells.

Stephen I‐Hong Hsu, Dalia Cohen, Lawrence S. Kirschner et al. · Molecular and Cellular Biology · 1990 · 122 citations · Full text

Genetics, Molecular Biology, Gene Characterization +16

Distinct P-glycoprotein precursors are overproduced in independently isolated drug-resistant cell lines.

Lee M. Greenberger, Leonard Lothstein, Susan Band Horwitz · Proceedings of the National Academy of Sciences · 1988 · 97 citations · Full text

Molecular Pharmacology, Glycosylation, Individual Family Members +12