Kara van Aelst

The Helicase-Like Domains of Type III Restriction Enzymes Trigger Long-Range Diffusion Along DNA

Friedrich W. Schwarz, Julia I. Toth, Kara van Aelst et al. · Science · 2013 · 84 citations

Life Sciences, Genetics, Molecular Biology +17

Type III restriction enzymes communicate in 1D without looping between their target sites

Subramanian P. Ramanathan, Kara van Aelst, Alice Sears et al. · Proceedings of the National Academy of Sciences · 2009 · 65 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

5′ modifications to CRISPR–Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage

Grace Mullally, Kara van Aelst, Mohsin M. Naqvi et al. · Nucleic Acids Research · 2020 · 51 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Type III restriction enzymes cleave DNA by long-range interaction between sites in both head-to-head and tail-to-tail inverted repeat

Kara van Aelst, Julia I. Toth, Subramanian P. Ramanathan et al. · Proceedings of the National Academy of Sciences · 2010 · 49 citations · Full text

Life Sciences, Molecular Biology, Enzymology +8

Recombination Hotspots and Single-Stranded DNA Binding Proteins Couple DNA Translocation to DNA Unwinding by the AddAB Helicase-Nuclease

Joseph T.P. Yeeles, Kara van Aelst, Mark S. Dillingham et al. · Molecular Cell · 2011 · 45 citations · Full text

Life Sciences, Genetics, Molecular Biology +14