Kevin J. Fettes

Novel Hydrophobically Modified Asymmetric RNAi Compounds (sd-rxRNA) Demonstrate Robust Efficacy in the Eye

Michael Byrne, Radouil Tzekov, Yi Wang et al. · Journal of Ocular Pharmacology and Therapeutics · 2013 · 77 citations

Synthesis and nucleic-acid-binding properties of sulfamide- and 3′-N-sulfamate-modified DNAElectronic supplementary information (ESI) available: typical melting curves obtained from thermal denaturation of modified oligonucleotides with complementary DNA and RNA. See http://www.rsc.org/suppdata/p1/b1/b110603c/

Kevin J. Fettes, Nigel Howard, David T. Hickman et al. · Journal of the Chemical Society Perkin Transactions 1 · 2002 · 29 citations

Bioorganic Chemistry, Molecular Biology, Peptide Science +19

Mechanism of the sulfurisation of phosphines and phosphites using 3-amino-1,2,4-dithiazole-5-thione (xanthane hydride)

Jiří Hanusek, Mark A. Russell, Andrew P. Laws et al. · Organic & Biomolecular Chemistry · 2007 · 20 citations

Heterocyclic, Biochemistry, Natural Sciences +8

Probing the effect of a 3′-S-phosphorothiolate link on the conformation of a DNA:RNA hybrid; implications for antisense drug designElectronic supplementary information (ESI) available: diagram showing sulfur link, UV melting curves, sample PE-COSY spectra, further NOE intensity data. See: http://www.rsc.org/suppdata/cc/b2/b203582k/

Andrew P. G. Beevers, Kevin J. Fettes, Ian A. O’Neil et al. · Chemical Communications · 2002 · 17 citations

NMR and UV studies of 3′-S-phosphorothiolate modified DNA in a DNA : RNA hybrid dodecamer duplex; implications for antisense drug design

Andrew P. G. Beevers, Kevin J. Fettes, Ghalia Sabbagh et al. · Organic & Biomolecular Chemistry · 2003 · 15 citations