Rieke Alten

Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial

Josef S Smolen, André Beaulieu, Andrea Rubbert‐Roth et al. · The Lancet · 2008 · 1.4K citations

Medicine, Immunology, Pharmacology +16

Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre trial

Jürgen Braun, J. Brandt, Joachim Listing et al. · The Lancet · 2002 · 1.3K citations

Medicine, Clinical Sciences, Internal Medicine +7

Treatment of Rheumatoid Arthritis by Selective Inhibition of T-Cell Activation with Fusion Protein CTLA4Ig

Joel M. Kremer, René Westhovens, Marc Léon et al. · New England Journal of Medicine · 2003 · 1.1K citations · Full text

Life Sciences, Immunology, Pharmacotherapy +17

Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial

Cem Gabay, Paul Emery, Ronald van Vollenhoven et al. · The Lancet · 2013 · 673 citations

Life Sciences, Immunology, Pharmacotherapy +13

Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA Study

Tuulikki Sokka, Sergio Toloza, Maurizio Cutolo et al. · Arthritis Research & Therapy · 2009 · 477 citations · Full text

Life Sciences, Immunology, Internal Medicine +17