In vitro and ex vivo analyses of co-infections with swine influenza and porcine reproductive and respiratory syndrome viruses

Irina Dobrescu, Benoît Levast, Ken Lai, +8

Veterinary Microbiology

Ex Vivo AnalysesVirologyPorcine ReproductivePorcine DiseaseSwine Virus +6

CpG Oligodeoxynucleotides Activate Innate Immune Response that Suppresses Infectious Bronchitis Virus Replication in Chicken Embryos

Arshud Dar, Andy Potter, Suresh K. Tikoo, +4

Avian Diseases

Viral ReplicationViral PathogenesisImmunologyImmune RegulationImmunologic Mechanism +15

Porcine TLR8 and TLR7 are both activated by a selective TLR7 ligand, imiquimod

Jianzhong Zhu, Ken Lai, Robert Brownile, +2

Molecular Immunology

Molecular ImmunologySelective Tlr7 LigandMedicineImmunologyAntigen Processing +7

Activation of adjuvant core response genes by the novel adjuvant PCEP

Sunita Awate, Heather L. Wilson, Ken Lai, +2

Molecular Immunology

ImmunogeneticsSignal TransductionMolecular PhysiologySignaling PathwayImmunology +8

Chlamydia suis and Chlamydia trachomatis induce multifunctional CD4 T cells in pigs

Tobias Käser, J. Alex Pasternak, Mario Delgado-Ortega, +7

Vaccine

Autoimmune DiseaseChlamydia TrachomatisT-regulatory CellPathogenesisImmunology +5

Administration of poly[di(sodium carboxylatoethylphenoxy)]phosphazene (PCEP) as adjuvant activated mixed Th1/Th2 immune responses in pigs

Arshud Dar, Ken Lai, Donna Dent, +4

Veterinary Immunology and Immunopathology

InflammationSodium CarboxylatoethylphenoxyImmunotoxicologyMedicineImmune Regulation +5

Response of immune response genes to adjuvants poly [di(sodium carboxylatoethylphenoxy)phosphazene] (PCEP), CpG oligodeoxynucleotide and emulsigen at intradermal injection site in pigs

Royford Magiri, Ken Lai, Alyssa Chaffey, +4

Veterinary Immunology and Immunopathology

Veterinary VaccineMucosal VaccinationAllergyAutoimmune DiseaseImmune Regulation +8

Intradermal immunization with inactivated swine influenza virus and adjuvant polydi(sodium carboxylatoethylphenoxy)phosphazene (PCEP) induced humoral and cell-mediated immunity and reduced lung viral titres in pigs

Royford Magiri, Ken Lai, Alyssa Chaffey, +5

Vaccine

VaccinationMucosal VaccinationVeterinary VaccineImmunologyVirology +8

Attenuated cytokine responses in porcine lymph node cells stimulated with CpG DNA are associated with low frequency of IFNα-producing cells and TLR9 mRNA expression

Arshud Dar, Anil Nichani, Ponn Benjamin, +6

Veterinary Immunology and Immunopathology

Transcriptional RegulationCpg DnaImmune Cell DevelopmentMedicineImmunology +9

Flow cytometry as an improved method for the titration of <i>Chlamydiaceae</i> and other intracellular bacteria

Tobias Käser, J. Alex Pasternak, Glenn Hamonic, +5

Cytometry Part A

Improved MethodPathogen DetectionPathologyMicrobial PhysiologyCyanobacteria +15