Onur Özcan

In silico identification of widely used and well-tolerated drugs as potential SARS-CoV-2 3C-like protease and viral RNA-dependent RNA polymerase inhibitors for direct use in clinical trials

Şeref Gül, Onur Özcan, Sinan Aşar et al. · Journal of Biomolecular Structure and Dynamics · 2020 · 69 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

Discovery of a small molecule that selectively destabilizes Cryptochrome 1 and enhances life span in p53 knockout mice

Şeref Gül, Yasemin Kübra Akyel, Zeynep Melis Gül et al. · Nature Communications · 2022 · 36 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

The Arg-293 of Cryptochrome1 is responsible for the allosteric regulation of CLOCK-CRY1 binding in circadian rhythm

Şeref Gül, Onur Özcan, Berke Gurkan et al. · Journal of Biological Chemistry · 2020 · 25 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Transcriptome analysis of the circadian clock gene BMAL1 deletion with opposite carcinogenic effects

Handan Emisoglu-Kulahli, Şeref Gül, Hande Morgil et al. · Functional & Integrative Genomics · 2020 · 20 citations

Life Sciences, Genetics, Molecular Biology +16

TW68, cryptochromes stabilizer, regulates fasting blood glucose levels in diabetic ob/ob and high fat-diet-induced obese mice

Saliha Sürme, Cagla Ergun Ayva, Şeref Gül et al. · Biochemical Pharmacology · 2023 · 12 citations

Life Sciences, Endocrinology, Physiology +13