Darren Fayne

Moisture Stable Dialkylimidazolium Salts as Heterogeneous and Homogeneous Lewis Acids in the Diels-Alder Reaction

Joshua Howarth, Keith Hanlon, Darren Fayne et al. · Tetrahedron Letters · 1997 · 238 citations

Chemical Engineering, Engineering, Homogeneous Lewis Acids +4

Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries

Henrike Veith, Noel Southall, Ruili Huang et al. · Nature Biotechnology · 2009 · 214 citations · Full text

Chemical Biology, Aldehyde Dehydrogenase, Biochemistry +5

Macrophage Migration Inhibitory Factor (MIF) Enzymatic Activity and Lung Cancer

Leona Mawhinney, Michelle E. Armstrong, Ciaran O’Reilly et al. · Molecular Medicine · 2014 · 65 citations · Full text

“True” Antiandrogens—Selective Non-Ligand-Binding Pocket Disruptors of Androgen Receptor–Coactivator Interactions: Novel Tools for Prostate Cancer

Laura Caboni, Gemma K. Kinsella, Fernando Blanco et al. · Journal of Medicinal Chemistry · 2012 · 55 citations · Full text

Androgen Receptor, Drug Target, Pharmacotherapy +21

The antidepressants maprotiline and fluoxetine have potent selective antiproliferative effects against Burkitt lymphoma independently of the norepinephrine and serotonin transporters

Suzanne M. Cloonan, Aleksandra Drozgowska, Darren Fayne et al. · Leukemia & lymphoma/Leukemia and lymphoma · 2010 · 47 citations

Selective Antiproliferative Effects, Chemoprevention Strategy, Medicine +14