Emily Hoyt

Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors

Kirsten McAulay, Emily Hoyt, Morgan Thomas et al. · Journal of the American Chemical Society · 2020 · 77 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Adaptive Optimization of Chemical Reactions with Minimal Experimental Information

Daniel Reker, Emily Hoyt, Gonçalo J. L. Bernardes et al. · Cell Reports Physical Science · 2020 · 76 citations · Full text

Computing, Chemistry, Computer Science +14

Controlled masking and targeted release of redox-cycling ortho-quinones via a C–C bond-cleaving 1,6-elimination

Lavinia Dunsmore, Claudio D. Navo, Julie Becher et al. · Nature Chemistry · 2022 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Stable Pyrrole‐Linked Bioconjugates through Tetrazine‐Triggered Azanorbornadiene Fragmentation

Enrique Gil de Montes, Alena Istrate, Claudio D. Navo et al. · Angewandte Chemie International Edition · 2020 · 27 citations · Full text

Pharmacy, Biotechnology, Chemical Biology +15

Single Mutation on Trastuzumab Modulates the Stability of Antibody–Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

Xhenti Ferhati, Ester Jiménez‐Moreno, Emily Hoyt et al. · Journal of the American Chemical Society · 2022 · 26 citations · Full text

Pharmacy, Oncology, Pharmacology +17