Thomas Winans

Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial

Zhi‐Wei Lai, Ryan L. Kelly, Thomas Winans et al. · The Lancet · 2018 · 390 citations

Rheumatology, Autoimmune Disease, Systemic Lupus Erythematosus Treatment +9

Mitochondrial Dysfunction in the Liver and Antiphospholipid Antibody Production Precede Disease Onset and Respond to Rapamycin in Lupus‐Prone Mice

Zachary Oaks, Thomas Winans, Tiffany Caza et al. · Arthritis & Rheumatology · 2016 · 130 citations · Full text

Rab4A-directed endosome traffic shapes pro-inflammatory mitochondrial metabolism in T cells via mitophagy, CD98 expression, and kynurenine-sensitive mTOR activation

Nick Huang, Thomas Winans, Brandon Wyman et al. · Nature Communications · 2024 · 60 citations · Full text

Cytosolic aldose metabolism contributes to progression from cirrhosis to hepatocarcinogenesis

Zachary Oaks, Akshay Patel, Nick Huang et al. · Nature Metabolism · 2023 · 41 citations · Full text

Hepatology, Metabolism Contributes, Hepatocellular Carcinoma +13

mTOR-dependent loss of PON1 secretion and antiphospholipid autoantibody production underlie autoimmunity-mediated cirrhosis in transaldolase deficiency

Thomas Winans, Zachary Oaks, G. Choudhary et al. · Journal of Autoimmunity · 2023 · 31 citations · Full text

Pon1 Secretion, Signal Transduction, Autoimmune Disease +14