Alexander Breuning

A New Lead for Nonpeptidic Active-Site-Directed Inhibitors of the Severe Acute Respiratory Syndrome Coronavirus Main Protease Discovered by a Combination of Screening and Docking Methods

Ulrich Kaeppler, Nikolaus Stiefl, Markus Schiller et al. · Journal of Medicinal Chemistry · 2005 · 58 citations

Michael Acceptor Based Antiplasmodial and Antitrypanosomal Cysteine Protease Inhibitors with Unusual Amino Acids

Alexander Breuning, Björn Degel, F. A. Schulz et al. · Journal of Medicinal Chemistry · 2010 · 51 citations · Full text

Bioorganic Chemistry, Antiparasitic Agent, Protease Inhibition +18

An improved synthesis of aziridine-2,3-dicarboxylates via azido alcohols—epimerization studies

Alexander Breuning, Radim Vičík, Tanja Schirmeister · Tetrahedron Asymmetry · 2003 · 47 citations

Organic Chemistry, Azido Alcohols—epimerization Studies, Pharmacology +1

Screening of Protease Inhibitors as Antiplasmodial Agents. Part I: Aziridines and Epoxides

F. A. Schulz, Christoph Gelhaus, Björn Degel et al. · ChemMedChem · 2007 · 46 citations

Screening of electrophilic compounds yields an aziridinyl peptide as new active-site directed SARS-CoV main protease inhibitor

Erika Martina, Nikolaus Stiefl, Björn Degel et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 41 citations · Full text

Electrophilic Compounds Yields, Biochemistry, Aziridinyl Peptide +8