Ryuji Oshima

VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease

Emiko Miura, Takafumi Hasegawa, Masatoshi Konno et al. · Neurobiology of Disease · 2014 · 194 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Synaptic Signaling +7

In vivo visualization of tau deposits in corticobasal syndrome by ¹⁸ F-THK5351 PET

Akio Kikuchi, Nobuyuki Okamura, Takafumi Hasegawa et al. · Neurology · 2016 · 109 citations · Full text

Lys-63-linked Ubiquitination by E3 Ubiquitin Ligase Nedd4-1 Facilitates Endosomal Sequestration of Internalized α-Synuclein

Naoto Sugeno, Takafumi Hasegawa, Nobuyuki Tanaka et al. · Journal of Biological Chemistry · 2014 · 69 citations · Full text

Neurodegenerative Diseases, Protein Function, Lys-63-linked Ubiquitination +11

ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways

Ryuji Oshima, Takafumi Hasegawa, Keiichi Tamai et al. · Scientific Reports · 2016 · 67 citations · Full text

Improvement of Freezing of Gait in Patients with Parkinson's Disease by Imagining Bicycling

Akio Kikuchi, Toru Baba, Takafumi Hasegawa et al. · Case Reports in Neurology · 2014 · 15 citations · Full text

Gait Start, Gait Analysis, Kinesiology +13