Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo

Deheng Chen, Dongdong Xia, Zongyou Pan, +15

Cell Death and Disease

Melatonin modulates IL-1β-induced extracellular matrix remodeling in human nucleus pulposus cells and attenuates rat intervertebral disc degeneration and inflammation

Yan Zhang, Fan He, Zhi Chen, +6

Aging

ImmunologyImmune RegulationCell DeathInnate ImmunityImmune System +20

Oxidative damage induces apoptosis and promotes calcification in disc cartilage endplate cell through ROS/MAPK/NF-κB pathway: Implications for disc degeneration

Yingchao Han, Xinhua Li, Meijun Yan, +5

Biochemical and Biophysical Research Communications

InflammationMusculoskeletal ResearchMedicineApoptosisCartilage Degeneration +9

A self-amplifying loop of YAP and SHH drives formation and expansion of heterotopic ossification

Cong Qian, Yuchen Liu, Taifeng Zhou, +14

Science Translational Medicine

Analysis and improvement of the three-column spinal theory

Qihang Su, Cong Li, Yongchao Li, +10

BMC Musculoskeletal Disorders

3D Computed Tomography Mapping of Thoracolumbar Vertebrae Fractures

Qihang Su, Yan Zhang, Shenghui Liao, +5

Medical Science Monitor

Single-cell RNA-seq analysis reveals that immune cells induce human nucleus pulposus ossification and degeneration

Song Guo, Meijun Yan, Xinhua Li, +7

Frontiers in Immunology

Three-dimensional computed tomography mapping of posterior malleolar fractures

Qihang Su, Juan Liu, Yan Zhang, +5

World Journal of Clinical Cases

βig-h3 enhances chondrogenesis via promoting mesenchymal condensation in rat Achilles tendon heterotopic ossification model

Qiang Zhang, Yan Zhang, Meijun Yan, +6

Aging

Pretreatment Computed Tomography-Based Machine Learning Models to Predict Outcomes in Hepatocellular Carcinoma Patients who Received Combined Treatment of Trans-Arterial Chemoembolization and Tyrosine Kinase Inhibitor

Qianqian Ren, Peng Zhu, Changde Li, +4

Frontiers in Bioengineering and Biotechnology