Khalid Abu Ajaj

Development of Novel Bisphosphonate Prodrugs of Doxorubicin for Targeting Bone Metastases That Are Cleaved pH Dependently or by Cathepsin B: Synthesis, Cleavage Properties, and Binding Properties to Hydroxyapatite As Well As Bone Matrix

Katrin Hochdörffer, Khalid Abu Ajaj, Cynthia Schäfer-Obodozie et al. · Journal of Medicinal Chemistry · 2012 · 101 citations

Sclerostin, Pharmacotherapy, Novel Bisphosphonate Prodrugs +20

A Toll-like receptor 2–integrin β3 complex senses bacterial lipopeptides via vitronectin

Gisa Gerold, Khalid Abu Ajaj, Michael Bienert et al. · Nature Immunology · 2008 · 84 citations

Toll-like Receptors, Microbial Pathogens, Medicine +7

In vitro and in vivo study of an albumin-binding prodrug of doxorubicin that is cleaved by cathepsin B

Khalid Abu Ajaj, Ralph Graeser, Iduna Fichtner et al. · Cancer Chemotherapy and Pharmacology · 2009 · 52 citations

Vivo Study, Molecular Pharmacology, Medicinal Chemistry +9

Development of Protein-Binding Bifunctional Linkers for a New Generation of Dual-Acting Prodrugs

Khalid Abu Ajaj, Martin L. Biniossek, Felix Kratz · Bioconjugate Chemistry · 2009 · 49 citations

Thiol-binding Prodrug, Dual-acting Prodrugs, Bioorganic Chemistry +19

Development of a novel prodrug of paclitaxel that is cleaved by prostate-specific antigen: An in vitro and in vivo evaluation study

Bakheet Elsadek, Ralph Graeser, N. Esser et al. · European Journal of Cancer · 2010 · 45 citations

Urology, Polymer-drug Conjugate, Medicine +8