A rapid on-line method for mass spectrometric confirmation of a cysteine-conjugated antibody-drug-conjugate structure using multidimensional chromatography

Robert E. Birdsall, Henry Shion, Frank W. Kotch, +3

mAbs

Pharmaceutical ScienceMedicinal ChemistryRapid On-line MethodDrug PurityBioanalysis +20

A sensitive multidimensional method for the detection, characterization, and quantification of trace free drug species in antibody-drug conjugate samples using mass spectral detection

Robert E. Birdsall, Sean M. McCarthy, Marie Claire Janin-Bussat, +4

mAbs

Drug TargetEngineeringMass Spectral DetectionConjugation ProcessesMedicinal Chemistry +23

Reduction of metal adducts in oligonucleotide mass spectra in ion‐pair reversed‐phase chromatography/mass spectrometry analysis

Robert E. Birdsall, Martin Gilár, Henry Shion, +2

Rapid Communications in Mass Spectrometry

Effects of Lead and Mercury on the Blood Proteome of Children

Robert E. Birdsall, Michael P. Kiley, Zaneer M. Segu, +8

Journal of Proteome Research

Lead IdentificationHeavy Metal ExposureLead PoisoningEnvironmental HealthBioanalysis +18

Ion-pair reversed-phase and hydrophilic interaction chromatography methods for analysis of phosphorothioate oligonucleotides

Martin Gilár, Brooke M. Koshel, Robert E. Birdsall

Journal of Chromatography A

Mer ImpuritiesMolecular BiologyIon-pair Reversed-phaseProtein PurificationPhosphorothioate Oligonucleotides +18

RPLC of Intact Proteins Using Sub-0.5 μm Particles and Commercial Instrumentation

Benjamin J. Rogers, Robert E. Birdsall, Zhen Wu, +1

Analytical Chemistry

NanoparticlesColloidal MaterialNanotherapeuticsEngineeringCommercial Instrumentation +23

Application of mobile phase additives to reduce metal-ion mediated adsorption of non-phosphorylated peptides in RPLC/MS-based assays

Robert E. Birdsall, Jacob Kellett, Ying Yu, +1

Journal of Chromatography B

EngineeringPeptide EngineeringRplc/ms-based AssaysChemistryBioanalysis +16

Two-dimensional liquid chromatography coupled to mass spectrometry for impurity analysis of dye-conjugated oligonucleotides

Brooke M. Koshel, Robert E. Birdsall, Weibin Chen

Journal of Chromatography B

Modeling of protein electrophoresis in silica colloidal crystals having brush layers of polyacrylamide

Robert E. Birdsall, Brooke M. Koshel, Yimin Hua, +2

Electrophoresis

Colloidal MaterialEngineeringNanoporous MaterialMillimeter DimensionsProtein Phase Separation +16

High-Throughput Analysis of Fluorescently Labeled N-Glycans Derived from Biotherapeutics Using an Automated LC-MS-Based Solution

Ximo Zhang, Corey E. Reed, Robert E. Birdsall, +1

SLAS TECHNOLOGY