Zuberwasim Sayyad

661W is a retinal ganglion precursor-like cell line in which glaucoma-associated optineurin mutants induce cell death selectively

Zuberwasim Sayyad, Kapil Sirohi, Vegesna Radha et al. · Scientific Reports · 2017 · 98 citations · Full text

A glaucoma‐ and ALS‐associated mutant of OPTN induces neuronal cell death dependent on Tbk1 activity, autophagy and ER stress

Swetha Medchalmi, Priyanka Tare, Zuberwasim Sayyad et al. · FEBS Journal · 2021 · 37 citations · Full text

Motor Neuron Disease, Apoptosis, Cell Death +16

Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer

Mohammad Afsar, Guanqun Liu, Lijia Jia et al. · Nature Communications · 2023 · 24 citations · Full text

Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication

Taryn M. Serman, Cindy Chiang, Guanqun Liu et al. · Cell Host & Microbe · 2023 · 22 citations · Full text

Virus Structure, Viral Replication, Molecular Virology +12

A glaucoma‐associated <scp>OPTN</scp> polymorphism, <scp>M98K</scp> sensitizes retinal cells to endoplasmic reticulum stress and tumour necrosis factor α

Zuberwasim Sayyad, Sreeram Kaveti, Debanjan Bhattacharjee et al. · FEBS Journal · 2023 · 18 citations · Full text

Ocular Disease, Immunology, Pathology +21