Kai Le

SIRT1-regulated HMGB1 release is partially involved in TLR4 signal transduction: A possible anti-neuroinflammatory mechanism of resveratrol in neonatal hypoxic-ischemic brain injury

Kai Le, Enkhmurun Chibaatar, Shanshan Wu et al. · International Immunopharmacology · 2019 · 98 citations

Inflammation, Reductive Stress, Possible Anti-neuroinflammatory Mechanism +15

Quercetin alleviates neonatal hypoxic-ischemic brain injury by inhibiting microglia-derived oxidative stress and TLR4-mediated inflammation

Kai Le, Zhiping Song, Jie Deng et al. · Inflammation Research · 2020 · 79 citations

Inflammation, Cerebral Vascular Regulation, Microglia-derived Oxidative Stress +13

Resveratrol Improves Synaptic Plasticity in Hypoxic-Ischemic Brain Injury in Neonatal Mice via Alleviating SIRT1/NF-κB Signaling–Mediated Neuroinflammation

Xin Peng, Jun Wang, Juan Peng et al. · Journal of Molecular Neuroscience · 2021 · 43 citations

Inflammation, Synaptic Plasticity, Hypoxic-ischemic Brain Injury +10

Alarmin HMGB1 Plays a Detrimental Role in Hippocampal Dysfunction Caused by Hypoxia-Ischemia Insult in Neonatal Mice: Evidence from the Application of the HMGB1 Inhibitor Glycyrrhizin

Kai Le, Shanshan Wu, Enkhmurun Chibaatar et al. · ACS Chemical Neuroscience · 2020 · 35 citations

Hmgb1 Inhibitor Glycyrrhizin, Oxidative Stress, Neuroinflammation +21

Chronic Unexpected Mild Stress Destroys Synaptic Plasticity of Neurons through a Glutamate Transporter, GLT-1, of Astrocytes in the Ischemic Stroke Rat

Dafan Yu, Zhenxing Cheng, Idriss Ali Abdoulaye et al. · Neural Plasticity · 2019 · 29 citations · Full text