Nynke I. Kramer

Predicting Adult Fish Acute Lethality with the Zebrafish Embryo: Relevance of Test Duration, Endpoints, Compound Properties, and Exposure Concentration Analysis

Melanie Knöbel, F Busser, Ángeles Rico-Rico et al. · Environmental Science & Technology · 2012 · 158 citations

Toxicology Testing, Toxicological Mechanism, Embryology +17

PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment

Jos Bessems, George Loizou, Kannan Krishnan et al. · Regulatory Toxicology and Pharmacology · 2013 · 145 citations · Full text

Animal Testing, Animal-free Risk Assessment, Physiologically Based Pharmacokinetics +10

Quantifying Processes Determining the Free Concentration of Phenanthrene in Basal Cytotoxicity Assays

Nynke I. Kramer, Mirna Krismartina, Ángeles Rico-Rico et al. · Chemical Research in Toxicology · 2012 · 139 citations

Free Concentration, Serum Protein, Pharmacological Study +14

Biokinetics in repeated-dosing in vitro drug toxicity studies

Nynke I. Kramer, Emma Di Consiglio, Bas J. Blaauboer et al. · Toxicology in Vitro · 2015 · 106 citations · Full text

Medicine, Toxicology, Pharmacology +2

Acute toxicity of the cationic surfactant C12-benzalkonium in different bioassays: How test design affects bioavailability and effect concentrations

Yi Chen, Marc Geurts, Sascha B. Sjollema et al. · Environmental Toxicology and Chemistry · 2013 · 86 citations